![]() Fluconazole: We take it for granted today, but the leap from ketoconazole to fluconazole when it first came out was truly gigantic.Linezolid: 1) This is the only oxazolidinone antibiotic 2) I don’t know what “oxazolidinone” means, nor how to pronounce it 3) I do know that this is by far the most expensive oral antibiotic out there.Rifampin: You can pretty much guarantee that if a patient needs intravenous rifampin, he/she also needs an ID consult.Doxycycline: We’re heading into the “doxycycline deficiency” season here in New England.Clindamycin: What a wonderful drug this would be - effective for a whole range of things - if it weren’t for that nasty C diff problem.2) A ID colleague of mine, who is married to a gastroenterologist, named her bird “Flagyl.” How perfect is that?!!! Metronidazole: 1) I am amazed that after decades of use of this drug, there is still no significant resistance among Bacteroides spp.Trimethoprim-sulfamethoxazole: 1) A double-strength tablet is gigantic, but it also comes in liquid form for the pill-averse 2) I always ask our ID fellows to tell me precisely (individual drugs and dose) what’s in a double-strength tablet of “Bactrim”, and about half of them know. ![]()
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